Michael Reese Endowed Professorship in Anesthesiology

Steven Roth, MD

I would like to thank the Foundation for providing funding which has enabled us to leverage for outside funding as shown. In addition to that shown here, an NIH grant with me as PI has been funded starting in the 17-18 year (Oct 17). The funding has enabled me to open up new areas of research (such as the one shown on exosomes).

I was further honored to be selected and receive additional funding from

the Michael Reese Pioneer in Research Award Program. I am grateful to the Foundation for this support!

Special Links:


https://ryortho.com/breaking/risk-of-spinal-fusion-related-blindness-dramatically- decreased/

http://uicscience.tumblr.com/post/146711093503/risk-of-blindness-from-spine- surgery-down

Conferences attended/spoken at:

Mohamed S, Mathew B, Torres L, Lopez J, Keil S, Stelman C, Schwartz A, Roth S (October 2016). Bone Marrow Mesenchymal Stem Cell Derived Exosomes Attenuate Ischemia Induced Retinal Injury. Conference: BMES 2016 Annual Meeting.

Roth S, Rubin DS, Moss HE, Joslin CE: Ischemic optic neuropathy in cardiac surgery. Society for Neuroscience in Anesthesia, Chicago, IL 2016

ION in Cardiac Surgery. S Roth. Upper Midwest Neuro-ophthalmology Group, Chicago, IL 2016

Roth S, Rubin DS, Moss HE, Joslin CE: Ischemic optic neuropathy in cardiac surgery. American Academy of Neurology, 2017

Roth S, Rubin DS, Moss HE, Joslin CE: Risk factors for ischemic optic neuropathy in cardiac surgery. Association for Research in Vision and Ophthalmology, Baltimore, MD, 2017

Published papers:

Dreixler JC, Poston JN, Balyasnikov I, Shaikh AR, Tupper Y, Lesniak MS, Roth S: Conditioned media from hypoxic-preconditioned bone marrow stem cells provides delayed rescue after retinal ischemia. Investigative Ophthalmology and Visual Science. 57:3522-32, 2016

Rubin DS, Parakati I, Lee LA, Moss HE, Joslin CE, Roth S: Trends and risk factors in ischemic optic neuropathy after spine fusion from the Nationwide Inpatient Sample: 1998 to 2012. Anesthesiology 125:457-64, 2016 (accompanied by editorial by M. Todd, MD).

Calway T, Rubin DS, Moss HE, Joslin CE, Beckmann K, Roth S.: Retinal artery occlusion in cardiac surgery from the National Inpatient Sample: 1998 to 2013. Ophthalmology. 124:189-196, 2017.

Rubin DS, Matsumoto MM, Moss HE, Joslin CE, Tung A, Roth S. Ischemic Optic Neuropathy in Cardiac Surgery: Incidence and Risk Factors in the United States from the National Inpatient Sample 1998 to 2013. Anesthesiology. 2017 May;126(5):810-821.

Mathew B, Poston JN, Torres L, Dreixler JC, Balyasnikov I, Shaikh AR, Lesniak MS, Roth S: Delayed administration of bone marrow stem cells significantly improves the outcome after retinal ischemia in rats. Graefe Arch Clin Exp Ophthalmol. 2017 Aug;255(8):1581-1592.

Rubin DS, Matsumoto MM, Weinberg GA, Roth S: Local anesthetic toxicity in upper and lower extremity joint arthroplasty: Results from the National Inpatient Sample: 1998 to 2013. Regional Anesthesia and Pain Medicine, accepted, page proofs.

Academic Year July 1, 2016 – June 30, 2017 - Grants Funded:

Student Research Fellowship (Preceptor for Clara Stelman) Craig Foundation and Foundation for Anesthesia Ed and Research

$3500 (total) 05/16-08/16

Medical Student Research Fellowship

(Preceptor for Taylor Calway, Chicago Med School)

Foundation for Anesthesia Education and Research

$3000 06/16-08/16

Undergraduate Research Award UIC Mohansrinivas Chennakesavalu ($1000)


Medical Student Research Fellowship (Preceptor for Monica Sharma)

Craig Foundation

$3000 05/17-08/17


Mechanisms of collateral blood flow in stroke Gregory Christoforidis, MD, Radiology, U Chicago 10% effort as collaborator


Directing therapeutic exosomes to neuronal targets Chicago Biomedical Consortium

Co-PI with E. Bongarzone (UIC), and J. Leonard (Northwestern)

$250,000 7/17-7/19

Autophagy and retinal post-ischemic conditioning Illinois Society for Prevention of Blindness


7/17 to 6/18

Hypothermic care of the eye

UIC College of Engineering research fund

Co PI with John Hetling, PhD, Bioengineering, UIC

$35,000 6/16-5/17

Mechanisms of retinal post-ischemic conditioning

Illinois Society for Prevention of Blindness

$2500 7/16-6/17